_1591679222 1591679222 Hamid Shirkhanloo sahar.zi67@gmail.com Hamid Shirkhanloo Analytical Methods in Environmental Chemistry Journal AMECJournal 2645-5382 2645-5552 03 30 2020 3 01 10.24200/amecj.v3.i01 http://journal.amecj.com/index.php/AMECJ-01/issue/view/11 Anne Trégouët Trégouët Masoud Khaleghi Abbasabadi Pooya Gholami *© Nickel (Ni) is toxic effect on human body and must be determined in human blood samples. In this study, Ni ions separated and preconcentrated from blood samples based on magnetic Fe3O4-supported amine/amide-functionalized graphene oxide (Fe3O4@A/A-GO) nanoparticles by dispersive sonication micro solid phase extraction (DS- μ-SPE).  By procedure, 10 mg of Fe3O4@A/A-GO was dispersed in 10 mL of human blood samples with sonication for 5.0 min and then separated from liquid phase with magnetic accessory. The Ni ions was extracted based on amine/amide covalence bonding of Fe3O4@A/A-GO sorbent (Ni---: NH2). Then, the Ni ions back-extracted from Fe3O4@A/A-GO in low pH with nitric acid (0.2 mL, 0.3 M) which was  diluted with DW  up to 0.5 mL and finally, was determined by ET-AAS(peak area). The LOD, linear range (LR), enrichment factor (EF) and absorption capacity (AC) were obtained 35 ng L-1, 0.15 -7.2 μg L-1, 19.8 and 131.6 mg g-1, respectively.  03 25 2020 5 16 http://creativecommons.org/licenses/by/4.0 10.24200/amecj.v3.i01.96 http://journal.amecj.com/index.php/AMECJ-01/article/view/96 http://journal.amecj.com/index.php/AMECJ-01/article/download/96/170 http://journal.amecj.com/index.php/AMECJ-01/article/download/96/170 http://journal.amecj.com/index.php/AMECJ-01/article/download/96/171