_1656993527
1656993527
Hamid Shirkhanloo
sahar.zi67@gmail.com
Hamid Shirkhanloo
Analytical Methods in Environmental Chemistry Journal
AMECJournal
2645-5382
2645-5552
06
30
2022
5
02
10.24200/amecj.v5.i02
http://journal.amecj.com/index.php/AMECJ-01/issue/view/22
Determination of mercury values in urine and air of chloralkali workers by copper nanoparticles functionalized in carboxylic carbon nanotubes and the effects of mercury exposure on oxidative stress
Ali
Faghihi Zarandi
Somayyeh
Karami-Mohajeri
Morteza
Mehdipour Rabouri
Abbas
Mohammadhosseini- Heyran
Zahed
Ahmadi
Mercury exposure can produce toxic organic compounds in the body. Also, mercury can potentially cause oxidative damage and cellular disorders. In this study, the determination of mercury values in urine and air of chloralkali workers based on copper nanoparticles functionalized in carboxylic carbon nanotubes (CuNPs@CNT-COOH) were obtained by cold vapor atomic absorption spectrometer (CV-AAS). The urine samples were determined by magnetic solid-phase extraction (MSPE) at pH 8.0. By measuring the mercury level in the air and the urine sample of workers, the level of oxidative stress (Malondialdehyde (MDA), Superoxide Dismutase (SOD) and Catalase (Cat)), Interleukin-6 (IL-6), and Tumor Necrosis Factor α (TNF-α) as the proinflammatory cytokines were measured in the subject group. The results revealed statistically significant differences in the mercury level of the urine samples in the case and control groups (p<0.001). Similarly, the malondialdehyde (MDA) level was significantly different between the two research groups (p<0.001). Catalase concentration was not significantly different in the two groups (p=0.059). The LOD and linear range for mercury determination in urine were achieved at 0.012 µg L−1 and 0.05-7.0 µg L−1, respectively. Workers’ exposure to mercury can significantly increase oxidative stress and inflammatory cell signaling molecules such as cytokines.
06
30
2022
76
89
http://creativecommons.org/licenses/by/4.0
10.24200/amecj.v5.i02.188
http://journal.amecj.com/index.php/AMECJ-01/article/view/188
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http://journal.amecj.com/index.php/AMECJ-01/article/download/188/416
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http://journal.amecj.com/index.php/AMECJ-01/article/download/188/416
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http://journal.amecj.com/index.php/AMECJ-01/article/download/188/417